Which compound is crucial for electron transport during the Citric Acid Cycle?

The compound that plays a crucial role in electron transport during the Citric Acid Cycle is FADH2. This molecule is one of the key energy carriers generated within the cycle. During several steps of the Citric Acid Cycle, specifically during the conversion of succinate to fumarate, FAD is reduced to form FADH2. This process is vital as FADH2, along with NADH, feeds into the electron transport chain located in the inner mitochondrial membrane.

FADH2 provides electrons that are ultimately transferred to oxygen, allowing for the production of ATP through oxidative phosphorylation. Each molecule of FADH2 contributes to the generation of approximately 1.5 ATP molecules due to its lower reduction potential compared to NADH, which yields about 2.5 ATP per molecule when it feeds its electrons into the electron transport chain.

In contrast, while NADH is also an electron carrier that plays a vital role in the cycle, your specific question centers on identifying the crucial compound for electron transport; FADH2’s unique position and function make it the primary focus in this context. ATP is the main energy currency of the cell but does not directly participate in the electron transport chain. Coenzyme A is essential for the formation of